Endocrine Abstracts

A 55-year-old lady was referred by her GP to the acute medical unit with a 4-week history of fatigue, generalised swelling and weight gain of a stone, together with a potassium 2.8 mmol/l and sodium 146 mmol/l. Her blood pressure was 211/85 mmHg and she was suspected of having Conn’s syndrome. Treatment was started with Amlodipine 5 mg daily and Spironolactone 25 mg daily which was increased to 100 mg daily on subsequent follow-up in the acute medical unit. She remained u...

62 year-old lady with a long history of hypokalaemia, hypertension and a random aldosterone of 786 pmol/l with suppressed renin of <8.0 mU/l at a time when she was taking Nebivolol, perindopril and Felodipine. Her Hypokalaemia improved after addition of Spironolactone and remained above 3.5 mmol/l. Biochemical work up confirmed a diagnosis of Conn’s syndrome and her BP control improved after addition of Aldosterone antagonist as above. Adrenal MRI revealed a 13 mm adr...

We present the case of a young man who had been known to the endocrine department with difficult to control hyperthyroidism and atrial fibrillation. After a period of treatment with carbimazole, during which he missed several appointments, he was referred for radioactive iodine therapy, which was administered in January 2013. He failed to attend for follow-up appointments and continued to take carbimazole.He was subsequently referred to the acute medicin...

A 37-year-old Asian lady was diagnosed with T3 N1b Papillary carcinoma of the thyroid and operated in 1999. Post operatively she developed hypoparathyroidism and has been on regular calcium and thyroid hormone replacement.She was on her 5th pregnancy this year. She had 2 previous Caesarian sections and 1 normal vaginal delivery. She was referred to Good Hope Hospital for obstetric care & local tertiary centre for investigation of hypocalcaemia having...

Ovarian hyperthecosis is a rare cause of androgenic alopecia in postmenopausal women. The physiological levels of androgens, secreted by ovarian stromal cells, are greatly increased with hyperplastic or neoplastic transformation leading to possible clinical consequences.We report a case of 56-year-old woman with type 2 diabetes presenting with hirsuitism and a history of male pattern hair loss over a two-year period. Biochemistry showed elevated levels o...

Ovarian hyperthecosis is a rare cause of androgenic alopecia in postmenopausal women. The physiological levels of androgens, secreted by ovarian stromal cells, are greatly increased with hyperplastic or neoplastic transformation leading to possible clinical consequences.We report a case of a 56-year-old woman with type 2 diabetes presenting with hirsuitism and a history of male pattern hair loss over a two year period. Biochemistry showed elevated levels...